Careers

 Join Our Team

We are seeking talented professionals who are dedicated to innovation, and want to grow their career within a growing, dynamic, and supportive environment.

Chief Medical Officer

About 3D Signatures Inc.

3D Signatures (3DS) (TSXV:DXD; OTCQB:TDSGF; FSE:3D0) is a personalized medicine company with a proprietary software platform based on the three-dimensional analysis of chromosomal signatures. The technology is well developed and supported by 22 clinical studies on over 2,000 patients across 13 different cancers and Alzheimer’s disease. Depending on the desired application, this platform technology can measure the stage of disease, rate of progression of disease, drug efficacy, and drug toxicity. The technology is designed to predict the course of disease and to personalize treatment for the individual patient. For more information, visit the Company’s new website at http://www.3dsignatures.com.

Job Description

The company is searching for a Chief Medical Officer to ensure its continued success, and to assist the company in transforming its 3D Telomere Technology into a disruptive platform of diagnostic/prognostic tests that will become commercially attractive to clinically laboratory partners and diagnostic companies. 3DS is at the late stage of completing its validation work on the company’s proof of principle Hodgkin’s lymphoma test and it expects to identify a commercial partner in 2017. In addition, the company intends to evaluate additional clinical development opportunities for its technology in prostate cancer, multiple myeloma, lung cancer, Alzheimer’s disease and breast cancer to name a few. The CMO will be based in Toronto, Canada, and report to the CEO, also in Toronto. She/he will have responsibility for the clinical strategy, implementation of the clinical development and operations plan, as well as oversight of the daily operation of test/assay development projects. She/he will collaborate with key internal stakeholders such as the CBO, CFO, VP Clinical, Director Clinical Operations and external stakeholders including CROs, key opinion leaders, investors, analysts and the company’s Clinical and Scientific Advisory Board (CSAB), including the CSAB Chair and co-founder of 3DS. The Chief Medical Officer will join the company’s senior leadership team.

We seek candidates with the following qualifications:

  • MD with seven to ten years of industry in related fields, or PhD with direct industry experience.
  • Must demonstrate knowledge of the clinical development process for diagnostics/prognostics and have direct clinical research and managerial experience. Managing trials in cancer diagnostics/prognostics would be an asset.
  • Experience in developing clinical tests, including laboratory developed tests (LDTs) and in-vitro diagnostic devices (IVDs).
  • Knowledge of clinical trial management and data management.
  • Prior experience in clinical study design, implementation of protocols, review/interpretation of data is required. This could be obtained through prior work in the diagnostic or pharmaceutical industry.
  • Knowledge of regulatory paths and experience in seeking IVD approvals through FDA .
  • A detailed understanding of CAP/CLIA/ISO/GMP clinical laboratory standards and requirements for licensing.
  • A detailed understanding of oncology, and the relevance of clinical endpoints and how diagnostic/prognostic tests can aid in personalized medicine.
  • Documented knowledge of molecular imaging required (fluorescent in situ hybridizations, 3D imaging vs. 2D imaging as a minimum). Documented knowledge of quantitative imaging (fluorescent microscopy) is an asset.
  • Excellent oral and written communication skills, as well as interpersonal skills.

Major Duties and Responsibilities:

  • Provide strategic medical input into clinical development strategies for the company’s diagnostic/prognostic tests.
  • Design, direct and oversee the implementation of all clinical projects.
  • Ensure that the overall scientific and medical content of all clinical programs is sound and aligned with the company’s goals and actionable commercial outcomes.
  • Prepare clinical development plans with detailed timelines and institute properly approved clinical protocols.
  • Design scientifically rigorous and cost-effective clinical development programs for the desired diagnostic/prognostics tests. Present and defend protocols.
  • Implement clinical R&D programs, policies, SOPs and related directives.
  • Monitor study progress, leading the analyses and data evaluation process for progress reporting and presentations to senior management, CSAB and Board members.
  • Prepare or direct the preparation of various official and regulatory documents for Regulatory and other agencies or partners.
  • Manage design and application of medical ethics.
  • Recruit and manage multidisciplinary professionals and clinical scientists as well as support career and project advancement.
  • Review potential out-licensing opportunities. Support any needed due diligence and prepare/present medically sound strategy and plans associated with advanced opportunities.

Do you have the skills, experience and qualities we seek and want to advance your career with a rapidly growing company? If so, please share your resume/CV with us and include your preferred daytime contact information.

For inquiries or to submit an application please email Jason.flowerday@3dsignatures.com

Experience: MD with seven to ten years of industry in related fields, or PhD with direct industry experience.

Location: Toronto, Ontario

Term: Fulltime Employment

For Inquiries and to Submit an Application:
By email only to: jason.flowerday@3dsignatures.com

Clinical Lab Technologist/Lab Scientist

About 3D Signatures Inc.

3D Signatures (3DS) (TSXV:DXD; OTCQB:TDSGF; FSE:3D0) is a personalized medicine company with a proprietary software platform based on the three-dimensional analysis of chromosomal signatures. The technology is well developed and supported by 22 clinical studies on over 2,000 patients across 13 different cancers and Alzheimer’s disease. Depending on the desired application, this platform technology can measure the stage of disease, rate of progression of disease, drug efficacy, and drug toxicity. The technology is designed to predict the course of disease and to personalize treatment for the individual patient. For more information, visit the Company’s new website at http://www.3dsignatures.com.

Job Description

3D Signatures Inc. is currently seeking to hire Clinical Lab Technologists/ Lab Scientists (minimum 2 positions available) for the company’s Reference Laboratory located in downtown Toronto. Reporting to the company’s VP, Clinical Trials, the Technologist/Scientist will process patient samples from clinical trials, R&D projects and protocol optimization & improvement projects. The patient samples to be processed include human tissue sections, circulating tumor cells isolated from human blood, other human primary cells and mammalian cell lines. The samples will be processed using 3D Signatures Inc. proprietary Telomeres Technology, including combined 3D-Quantitative telomeres immuno-FISH, 2D/3D image acquisition using fluorescence microscopy and image analysis using the company’s proprietary software platform. The Technologist/Scientist will participate in routine group meetings, prepare presentations and present experimental data as needed.

Education & Experience (any of the listed below may be considered)

  • A PhD degree in genetics, cell or molecular biology or other related medical/clinical disciplines with 2-3 years of post doctoral training preferably in a clinical setting
  • BsC/M.SC in medical sciences or related discipline with 3 years of clinical laboratory experience
  • Formal postsecondary Medical/Clinical Laboratory training with 5 years of clinical laboratory experience
  • Clinical laboratory technologist designation/certification is a strong asset
  • Other relevant combinations of education and clinical laboratory experience may be considered

Skills & Knowledge: 

Required

  • Cell culture techniques: growing, maintaining and harvesting cell lines and human primary cells
  • Immunocytochemistry/ Immunohistochemistry techniques (on cells and tissue sections)
  • Fluorescence in situ hybridization (FISH) techniques (on cells and tissue sections)
  • 2-dimensional and 3-dimensional fluorescence image acquisition techniques
  • Experience with quantification of fluorescence signals and image analysis
  • Expert knowledge of Microsoft office software and Adobe Acrobat pro software

Preferred

  • Experience in image acquisition using Zeiss microscopes and Zeiss operating systems
  • Experience with combined immuno-FISH protocols
  • Experience with using e-lab books and/or document management systems
  • Experience in optimizing laboratory protocols and assay development
  • Experience working in CAP accredited/CLIA/ISO certified laboratories

Compensation: Salary will commensurate with qualifications and experience. 3D Signatures Inc. offers a comprehensive benefits package and a performance based incentive program

Please forward your resume and a cover letter describing how you meet or exceed the required skills & knowledge areas and experience by the outlined deadline.

We thank all applicants for their interest in 3D Signatures Inc., only applicants selected for interview will be contacted

3D Signatures Inc. is an equality employer. Applicants with disabilities or belonging to ethnic groups or visible minorities are welcomed to apply.

Location: Winnipeg, Manitoba

Term: Fulltime Employment

Start Date: March 15, 2017 (or a mutually agreed on date)

Deadline to Apply: February 17, 2016

For Inquiries and to Submit an Application:
By email only to: sherif.louis@3dsignatures.com

Software Developer – Image Processing & Analysis

About 3D Signatures Inc.

3D Signatures (3DS) (TSXV:DXD; OTCQB:TDSGF; FSE:3D0) is a personalized medicine company with a proprietary software platform based on the three-dimensional analysis of chromosomal signatures. The technology is well developed and supported by 22 clinical studies on over 2,000 patients across 13 different cancers and Alzheimer’s disease. Depending on the desired application, this platform technology can measure the stage of disease, rate of progression of disease, drug efficacy, and drug toxicity. The technology is designed to predict the course of disease and to personalize treatment for the individual patient. For more information, visit the Company’s new website at http://www.3dsignatures.com.

Job Description

3D Signatures Inc. is currently seeking a Software Developer to be responsible for designing and integrating clinical imaging and image analysis of software & software platform solutions, applications and improvements to meet the company’s needs and/or industry standard requirements. The role will include the design of high quality software systems (code, unit tests, flowcharts, timing diagrams, memory analysis, etc.), integration of software systems with other modules/system (mechanical, electrical, software), and the development of software system and project related documentation (e.g. design specifications, detailed designs, work instructions, test plans and reports). This position will also be responsible for the ongoing monitoring and maintenance of software solutions that meet or exceed company, quality, regulatory and industry expectations.

Education:

Undergraduate University Degree in Computer Science, Microscopy or bioinformatics. A combination of background in life sciences microscopy imaging and formal graduate and/or post-graduate training in computer sciences and programing or the opposite is acceptable.

Skills & Knowledge:

Required
Fluent in C/C++/C# & Matlab software
Knowledge of VTK, ITK, & scripting languages
Experience with computer vision & image processing techniques
Knowledge of fluorescent microscopy imaging and related operating software
Experience with Iron Python script language

Preferred
Industry experience with ISO 13485, IEC 62304
Experience with GPU coding (CUDA or other)
Experience with machine learning algorithms
Knowledge of GIT, PHP, VLC Silverlight, DICOM, QT, GDCM
Ability to design software architectures
Experience with Carl Zeiss imaging and analysis software

Compensation: Salary will commensurate with qualifications and experience.
3D Signatures offers a comprehensive benefits package and a performance based incentive program.

Please forward your resume and a cover letter describing how you meet the required qualifications and experience on or before the outlined deadline

We thank all applicants for their interest in 3D Signatures. Please note, only applicants selected for interview will be contacted.

3D Signatures Inc. is an equality employer. Applicants with disabilities or belong to ethnic groups or visible minorities are welcomed to apply.

Experience: 3-5 years software developing experience

Location: Toronto, Ontario

Term: Fulltime Employment

Deadline to Apply: February 15, 2016

For Inquiries and to Submit an Application:
By email only to: sherif.louis@3dsignatures.com